VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

View Phenotyping Groups:

001

Data Science to Patient Value Initiative (D2V) - Colorado

Precision Medicine and Health Disparities Collaborative

Vanderbilt - Music Cognition Lab

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

Final

Breast Cancer

Breast cancer is the most common cancer and the second leading cause of cancer-related death among women in the U.S. Known breast cancer risk factors include age, race/ethnicity, reproductive factors, and benign breast disease. Family history of breast cancer and hereditary cancer syndromes, such as BRCA1/BRCA2 mutations, confer the strongest risk for this disease.

Owner Phenotyping Groups:

View Phenotyping Groups:

001

Data Science to Patient Value Initiative (D2V) - Colorado

Precision Medicine and Health Disparities Collaborative

Vanderbilt - Music Cognition Lab

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

VICTR Phenotyping

Final

Chronic Kidney Disease

Chronic kidney disease (CKD) is defined as an abnormality of kidney structure or function present for longer than 3 months. CKD can occur as a result of heterogeneous disorders affecting the kidney. In the United States, an estimated 13.6% of adults have CKD. Notably, adjusted mortality rates are higher for patients with CKD than those without, and rates increase with CKD stage. The purpose of this algorithm is to enable accurate CKD diagnosis and staging based on EHR data.

Owner Phenotyping Groups:

View Phenotyping Groups:

001

Data Science to Patient Value Initiative (D2V) - Colorado

Precision Medicine and Health Disparities Collaborative

Vanderbilt - Music Cognition Lab

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

Final

Clopidogrel Poor Metabolizers

Note: Attached documents contain full case definition and two different control definitions. One is for controls with 2 years of follow up, the other for controls with 1 year of follow up. All available controls with 2 years of follow up were used in Vanderbilt's study. The control population was supplemented by controls with only 1 year of follow up. At the time of study, many of the available controls had experienced their qualifying events somewhat recently and 2 years had not yet passed for full follow up.

Owner Phenotyping Groups:

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

View Phenotyping Groups:

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

Final

Colorectal Cancer (CRC)

A pheontype defining patients with strong evidence of having been diagnosed with colorectal cancer (cases) and patients who clearly do not have such diagnoses (controls). This phenotype is being used for sequencing studies. The only NLP involved in this phenotype is a very simple string search applied to pathology reports.

Owner Phenotyping Groups:

Final

Peanut Allergy

Food allergy is defined as an immune response that occurs reproducibly to a given food, typically an immunoglobulin E (IgE)-mediated clinical reaction to specific protein epitopes. Over the last 20-30 years, food allergy has grown into a major public health problem. Peanut allergy is a common type of food allergy that accounts for a disproportionate number of fatal and near-fatal anaphylactic events amongst all the common food allergens.

Owner Phenotyping Groups:

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

View Phenotyping Groups:

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

Final

Steroid Induced Osteonecrosis

View Phenotyping Groups:

VESPA - Vanderbilt Electronic Systems for Pharmacogenomic Assessment

Final

Type1 or Type 2 Diabetes Mellitus

Phenotyping algorithm for the identification of patients with type 1 or type 2 diabetes mellitus (DM) preoperatively using routinely available clinical data from electronic
health records.

View Phenotyping Groups:

Precision Medicine and Health Disparities Collaborative